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兔抗FBXO32多克隆抗體

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- 品牌 : 通蔚生物
- 目錄號 : TW20289
- 應用 : 僅供科研使用
- 保存條件 : 低溫保存
- 貨期 : 現(xiàn)貨
- 商品庫存：75
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中文名稱：兔抗FBXO32多克隆抗體

英文名稱： Anti-FBXO32 rabbit polyclonal antibody

別名： Fbx32; MAFbx

相關類別：一抗

抗原： FBXO32

儲存： 冷凍（-20℃）

宿主： Rabbit

反應種屬： Human, Mouse, Rat

標記物： Unconjugate

克隆類型： rabbit polyclonal

技術規(guī)格

Background:

This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class and contains an F-box domain. This protein is highly expressed during muscle atrophy, whereas mice deficient in this gene were found to be resistant to atrophy. This protein is thus a potential drug target for the treatment of muscle atrophy. Alternative splicing results in multiple transcript variants encoding different isoforms.

Applications:

ELISA, IHC

Name of antibody:

FBXO32

Immunogen:

Synthetic peptide corresponding to a region derived from 69-82 amino acids of human FBXO32

Full name:

F-box protein 32

Synonyms:

Fbx32; MAFbx

SwissProt:

Q969P5

ELISA Recommended dilution:

5000-10000

IHC Positive control:

Human liver cancer;Human prostate cancer

IHC Recommended dilution:

30-150

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Background:	This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class and contains an F-box domain. This protein is highly expressed during muscle atrophy, whereas mice deficient in this gene were found to be resistant to atrophy. This protein is thus a potential drug target for the treatment of muscle atrophy. Alternative splicing results in multiple transcript variants encoding different isoforms.
Applications:	ELISA, IHC
Name of antibody:	FBXO32
Immunogen:	Synthetic peptide corresponding to a region derived from 69-82 amino acids of human FBXO32
Full name:	F-box protein 32
Synonyms:	Fbx32; MAFbx
SwissProt:	Q969P5
ELISA Recommended dilution:	5000-10000
IHC Positive control:	Human liver cancer;Human prostate cancer
IHC Recommended dilution:	30-150

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兔抗FBXO32多克隆抗體