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中文名稱： 兔抗PTPRM多克隆抗體

英文名稱： Anti-PTPRM rabbit polyclonal antibody

別名： RPTPM, RPTPU, PTPRL1, hR-PTPu, R-PTP-MU

相關類別： 一抗

儲存： 冷凍（-20℃）

宿主： Rabbit

抗原： PTPRM

反應種屬： Human, Mouse

標記物： Unconjugate

克隆類型： rabbit polyclonal

技術規(guī)格

Background:	The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and two tandem catalytic domains, and thus represents a receptor-type PTP. The extracellular region contains a meprin-A5 antigen-PTP mu (MAM) domain, an Ig-like domain and four fibronectin type III-like repeats. This PTP has been shown to mediate cell-cell aggregation through the interaction with another molecule of this PTP on an adjacent cell. This PTP can interact with scaffolding protein RACK1/GNB2L1, which may be necessary for the downstream signaling in response to cell-cell adhesion. Alternative splicing results in multiple transcripts encoding distinct isoforms.
Applications:	ELISA, IHC
Name of antibody:	PTPRM
Immunogen:	Synthetic peptide of human PTPRM
Full name:	Protein tyrosine phosphatase, receptor type, M
Synonyms：	RPTPM, RPTPU, PTPRL1, hR-PTPu, R-PTP-MU
SwissProt:	P28827
ELISA Recommended dilution:	2000-10000
IHC positive control:	Human breast cancer and Human lung cancer
IHC Recommend dilution:	50-200