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中文名稱：兔抗MME多克隆抗體

英文名稱： Anti-MME rabbit polyclonal antibody

別名： NEP, SFE, CD10, CALLA

相關類別： 一抗

儲存： 冷凍（-20℃）

宿主： Rabbit

抗原： MME

反應種屬： Human, Mouse, Rat

標記物： Unconjugate

克隆類型： rabbit polyclonal

技術規(guī)格

Background:	This gene encodes a common acute lymphocytic leukemia antigen that is an important cell surface marker in the diagnosis of human acute lymphocytic leukemia (ALL). This protein is present on leukemic cells of pre-B phenotype, which represent 85% of cases of ALL. This protein is not restricted to leukemic cells, however, and is found on a variety of normal tissues. It is a glycoprotein that is particularly abundant in kidney, where it is present on the brush border of proximal tubules and on glomerular epithelium. The protein is a neutral endopeptidase that cleaves peptides at the amino side of hydrophobic residues and inactivates several peptide hormones including glucagon, enkephalins, substance P, neurotensin, oxytocin, and bradykinin. This gene, which encodes a 100-kD type II transmembrane glycoprotein, exists in a single copy of greater than 45 kb. The 5' untranslated region of this gene is alternatively spliced, resulting in four separate mRNA transcripts. The coding region is not affected by alternative splicing.
Applications:	ELISA, WB, IHC
Name of antibody:	MME
Immunogen:	Synthetic peptide of human MME
Full name:	membrane metallo-endopeptidase
Synonyms：	NEP, SFE, CD10, CALLA
SwissProt:	P08473
ELISA Recommended dilution:	2000-5000
IHC positive control:	Human colon cancer and Human lung cancer
IHC Recommend dilution:	25-100
WB Predicted band size:	86 kDa
WB Positive control:	293T cells
WB Recommended dilution:	500-2000