產品中心

中文名稱： KAZN 抗原（重組蛋白）

英文名稱： KAZN Antigen (Recombinant Protein)

別名： kazrin, periplakin interacting protein; KAZ

相關類別： 抗原

儲存：冷凍（-20℃）

概述

Fusion protein corresponding to a region derived from 626-775 amino acids of human KAZN

技術規(guī)格

Full name:	kazrin, periplakin interacting protein
Synonyms:	KAZ
Swissprot:	Q674X7
Gene Accession:	BC113621
Purity:	>85%, as determined by Coomassie blue stained SDS-PAGE
Expression system:	Escherichia coli
Tags:	His tag C-Terminus, GST tag N-Terminus
Background:	This gene encodes a protein that plays a role in desmosome assembly, cell adhesion, cytoskeletal organization, and epidermal differentiation. This protein co-localizes with desmoplakin and the cytolinker protein periplakin. In general, this protein localizes to the nucleus, desmosomes, cell membrane, and cortical actin-based structures. Some isoforms of this protein also associate with microtubules. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional splice variants have been described but their biological validity has not been verified.