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中文名稱：TRAF4 抗原（重組蛋白）

英文名稱： TRAF4 Antigen (Recombinant Protein)

別名： TNF receptor associated factor 4; CART1; MLN62; RNF83

儲存： 冷凍（-20℃）

相關類別： 抗原

概述：

Fusion protein corresponding to a region derived from 307-462 amino acids of human TRAF4

技術規(guī)格：

Full name:	TNF receptor associated factor 4
Synonyms:	CART1; MLN62; RNF83
Swissprot:	Q9BUZ4
Gene Accession:	BC001769
Purity:	>85%, as determined by Coomassie blue stained SDS-PAGE
Expression system:	Escherichia coli
Tags:	His tag C-Terminus, GST tag N-Terminus
Background:	This gene encodes a member of the TNF receptor associated factor (TRAF) family. TRAF proteins are associated with, and mediate signal transduction from members of the TNF receptor superfamily. The encoded protein has been shown to interact with neurotrophin receptor, p75 (NTR/NTSR1), and negatively regulate NTR induced cell death and NF-kappa B activation. This protein has been found to bind to p47phox, a cytosolic regulatory factor included in a multi-protein complex known as NAD(P)H oxidase. This protein thus, is thought to be involved in the oxidative activation of MAPK8/JNK. Alternatively spliced transcript variants have been observed but the full-length nature of only one has been determined.