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  • DOK1抗原(重組蛋白)

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    • 品牌 : 通蔚生物
    • 目錄號(hào) : TW10432
    • 應(yīng)用 : 僅供科研使用
    • 保存條件 : 低溫保存
    • 貨期 : 現(xiàn)貨
    • 商品庫(kù)存:75
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中文名稱:DOK1抗原(重組蛋白)

英文名稱:DOK1 Antigen (Recombinant Protein)

儲(chǔ)      存:冷凍(-20℃)

相關(guān)類別抗原

概述

Fusion protein corresponding to C terminal 300 amino acids of human DOK1


技術(shù)規(guī)格

Full name:

docking protein 1, 62kDa (downstream of tyrosine kinase 1)

Synonyms:

P62DOK

Swissprot:

Q99704

Gene Accession:

BC114440

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

The protein encoded by this gene is part of a signal transduction pathway downstream of receptor tyrosine kinases. The encoded protein is a scaffold protein that helps form a platform for the assembly of multiprotein signaling complexes. Two transcript variants encoding different isoforms have been found for this gene. DOK1 appears to be a negative regulator of the insulin signaling pathway. Modulates integrin activation by competing with talin for the same binding site on ITGB3.